Evidence map›Paper›PMID 42240856›Full record

ArticleCurrent microbiology2026

Deciphering the Genetic Mechanisms Driving Carbapenem Resistance: A Multicenter Study from Seven Egyptian Governorates Using Multiplex PCR and Whole Genome Sequencing.

Maha Gad, May Sherif, Sara Essam, Doaa Gamal, Inas El-Defrawy, Mohammed Abdelhakeem, Omnia Taher, Radwa Abdel-Latif, Ahmed Shoala, Sherine Shawky and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maha GadDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, 1 Al-Saray Str, Al-Manial, Cairo, 11559, Egypt. maha.gad@cu.edu.eg.ORCID http://orcid.org/0000-0002-7717-6747
May SherifDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, 1 Al-Saray Str, Al-Manial, Cairo, 11559, Egypt.
Sara EssamDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, 1 Al-Saray Str, Al-Manial, Cairo, 11559, Egypt.
Doaa GamalTheodor Bilharz Research Institute (TBRI), Giza, Egypt.
Inas El-DefrawyTheodor Bilharz Research Institute (TBRI), Giza, Egypt.
Mohammed AbdelhakeemClinical and Chemical Pathology Department, Minia University Hospitals, Minya, Egypt.
Omnia TaherDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Ain Shams University, Alabassya, Cairo, Egypt.
Radwa Abdel-LatifDepartment of Clinical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Ahmed ShoalaDepartment of Critical Care Unit, National Heart Institute, Cairo, Egypt.
Sherine ShawkyFaculty of Medicine, Alexandria University, Alexandria, Egypt.
Hebatallah RashedClinical Pathology Department, Faculty of Medicine, Assiut University Hospitals, Assiut, Egypt.
Hamida GoharMedical Microbiology and Immunology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Hadir El-MahallawyDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
Amani El-KholyDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, 1 Al-Saray Str, Al-Manial, Cairo, 11559, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant Enterobacterales (CRE) causing healthcare-associated infections (HAI) represent a growing public health threat. We conducted a large-scale multicenter study to characterize CRE isolates from ICU patients in Egypt. Non-repetitive CRE clinical isolates were collected from infected ICU patients in 10 tertiary hospitals across 7 governorates over one year. Identification and susceptibility testing were performed using VITEK-2. Carbapenemase genes were detected by multiplex PCR for bla

Indexed as

Anti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeCarbapenemsEnterobacteriaceae InfectionsBacterial Proteinsbeta-LactamasesCross InfectionEgyptGenome, BacterialHumansMicrobial Sensitivity TestsMultiplex Polymerase Chain ReactionWhole Genome SequencingAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenems

Identifiers

PMID42240856

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.