ArticleIn vitro cellular & developmental biology. Animal2026
Pesticides-induced cellular toxicity in the spinal cord cell line of Lates calcarifer.
Article in In vitro cellular & developmental biology. Animal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
Abstract
The extensive use of commercial pesticide formulations, often containing multiple active ingredients, has raised growing concerns about their potential environmental and human health impacts. Among the most widely applied pesticides are imidacloprid (IMI), λ-cyhalothrin (LCT), deltamethrin (DMN), and thiamethoxam (TMX). This study investigated the cytotoxic effects of acute exposure to commercial formulations of these compounds on a seabass spinal cord (SBSC) cell line. Cytotoxicity was evaluated using MTT and Neutral Red (NR) uptake assays, in conjunction with assessments of reactive oxygen species (ROS) generation, plasma membrane staining, lysosomal acidity, fluorescence-based cellular labelling, and effects on neurite-like outgrowth. Effective concentrations (EC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.