Evidence map›Paper›PMID 42240793›Full record

ArticleEJNMMI physics2026

Scan duration for dopamine transporter neuroimaging with[

Gerda Thomsen, Karine Madsen, Cecilie A Poulsen, Claus Svarer, Lars H Pinborg, Gitte M Knudsen, Robin de Nijs

Erratum issuedAbstract read
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gerda ThomsenNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. gerda@nru.dk.ORCID http://orcid.org/0009-0003-5827-5525
Karine MadsenDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Cecilie A PoulsenNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Claus SvarerNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Lars H PinborgNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Gitte M KnudsenNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Robin de NijsNeurobiology Research Unit, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDopamine transporter (DAT) imaging with [

methodsFifty patients suspected of parkinsonism (age range 52-87 years) and 9 healthy controls (age range 57-66 years) underwent imaging with Mediso AnyScan Trio SPECT/CT and MPH collimators for 40 min. three hours after injection of 185 MBq [

resultsCompared to 40 min. acquisitions and both in patients and healthy controls, 10 min acquisitions resulted in a significantly higher specific binding ratio (SBR) (≥ 0.5) in the striatum, putamen and caudate (p ≤ 0.001). SBR did not differ statistically significant between 30- and 40-min. acquisitions. Mean SBR difference between 20- and 40-min. scans with the 40-min. scan as a reference was 0.07 with 95% CI [-0.45, 0.59] for the striatum. Visual inspection of images showed that 20 min. acquisitions resulted in acceptable image quality (≥84% rated as sufficient).

conclusionWe find that the scan time with DAT SPECT imaging on SPECT/CT and MPH collimators can be reduced to 20 min. without compromising image quality and diagnostic outcome. A scan duration of 20 min is beneficial for both patient comfort and the clinical workflow.

Indexed as

AnyScandopamine transporterFP-CITioflupanemulti-pinhole collimatorscan durationSPECT

Identifiers

PMID42240793
PMCPMC13454077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.