Observational studySleep & breathing = Schlaf & Atmung2026
Association of obstructive airway disease with COMISA: findings from the Turkish sleep apnea database (TURKAPNE) cohort.
Observational study in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComorbid insomnia and sleep apnea (COMISA) is a highly burdensome phenotype with additive effects on symptoms, quality of life, and health outcomes. Although obstructive airway diseases (OAD)-including asthma and chronic obstructive pulmonary disease-commonly coexist with sleep complaints, the association between OAD and COMISA in large sleep-clinic cohorts remains unclear. We investigated whether OAD is independently associated with COMISA in a nationwide cohort undergoing full-night polysomnography (PSG).
methodsWe analyzed 12,715 adults in the Turkish Sleep Apnea Database (TURKAPNE), a prospective, multicenter registry. Demographics, comorbidities, insomnia symptoms, and PSG parameters were compared between individuals with and without OAD, defined as self-reported, physician-diagnosed asthma or COPD. COMISA was defined as the coexistence of obstructive sleep apnea (apnea-hypopnea index ≥ 5 events/h) and insomnia symptoms occurring "often" or "very often." Multivariable logistic regression was used to determine the independent association between OAD and COMISA.
resultsOAD was present in 12.2% of participants (n = 1,546). COMISA prevalence was higher in those with OAD than in those without OAD (16.1% vs 10.8%, p < 0.001). After adjustment for age, sex, body mass index, education, smoking status, and comorbidities, OAD remained independently associated with COMISA (adjusted odds ratio 1.19; 95% CI 1.06-1.35; p = 0.004). Among participants with COMISA, individuals with OAD were older, more frequently female, more obese, and demonstrated shorter total sleep time, longer wake after sleep onset, higher periodic limb movement index, and poorer nocturnal oxygenation.
conclusionsIn this nationwide sleep-clinic cohort, OAD was independently associated with COMISA. COMISA patients with OAD exhibited more adverse clinical and polysomnographic features. These findings highlight the multidimensional sleep burden in OAD and support integrated, personalized management strategies.
Indexed as
Identifiers
42240780What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.