Evidence map›Paper›PMID 42240754›Full record

ArticleVeterinary research communications2026

Corn processing methods associated with calcium salts of fatty acids and organic minerals preserve gastrointestinal epithelium and mitigates systemic inflammation in beef cattle fed high grain diets.

B L Demartini, A M Silvestre, L D Felizari, M M Squizatti, L A F Silva, D M Casali, O A Sousa, B J Johnson, A C J Pinto, D H M Watanabe and 1 more

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

B L DemartiniSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
A M SilvestreSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
L D FelizariSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
M M SquizattiSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
L A F SilvaSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
D M CasaliSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
O A SousaSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
B J JohnsonDepartment of Animal and Food Science, Texas Tech University, Lubbock, TX, USA.
A C J PintoSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
D H M WatanabeFaculty of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo, Brazil.
D D MillenFaculty of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo, Brazil. danilo.millen@unesp.br.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/24747-4
6 · The paper itself

Abstract

High-concentrate diets can impair gastrointestinal integrity and induce systemic inflammation in feedlot cattle. This study evaluated the effects of corn processing (finely ground corn [FGC] vs. high-moisture corn [HMC]) and supplementation with calcium salts of fatty acids (CSFA) and organic zinc/chromium (ZnCr) on gastrointestinal health and inflammatory responses. One hundred and fifty bulls were assigned to 30 pens in a randomized complete block design using a 2 × 2 + 1 factorial arrangement. Treatments included FGC, FGC+CSFA, HMC, HMC+CSFA, and HMC+CSFA+ZnCr. Cattle fed HMC showed reduced dry matter and starch intake (P < 0.01) and fecal starch on d 112 (P < 0.01), but greater rumenitis scores (P = 0.01) compared with FGC-fed cattle. CSFA supplementation reduced blood concentrations of haptoglobin (P = 0.04), LPS-binding protein (P = 0.04), and C-reactive protein (P = 0.03), as well as rumenitis scores (P = 0.03), while increasing ruminal papillae height (P = 0.03). Compared with HMC+CSFA, cattle receiving HMC+CSFA+ZnCr had lower fecal starch on d 56 (P = 0.02), greater ruminal papillae width (P = 0.03), and increased enterocyte density (P = 0.02). Overall, CSFA improved gut health and reduced systemic inflammation in cattle fed high-grain diets regardless of the corn processing.

Indexed as

Animal FeedAnimal Nutritional Physiological PhenomenaDietary SupplementsFatty AcidsFood HandlingGastrointestinal TractRumenZea maysAnimalsCalciumCattleCell CountDietEnterocytesInflammationMaleCalciumFatty AcidsMineralsChromiumCorn processingFatty acidsGut healthZinc

Identifiers

PMID42240754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.