Evidence map›Paper›PMID 42240720›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Head and neck cancer rehabilitation: the CaRe feasibility study.

Grainne Sheill, Sophie Grehan, Annemarie E Bennett, Conor Bowe, Julie Broderick, Kelly Coghlan, Julie Regan, Juliette Hussey, John Ed O Connell

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06646861 (Head and Neck Cancer Rehabilitation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06646861 nacompletednot on this map

Head and Neck Cancer Rehabilitation: The CaRe Feasibility Study

TypeinterventionalSponsorUniversity of Dublin, Trinity CollegeRan2024 to 2025Enrolled22ConditionsHead and Neck Cancer SurvivorsArmsExercise
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond feasibility: the case for lymphoedema-stratified rehabilitation trials in head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Grainne SheillUniversity of Dublin, Trinity College Dublin, Dublin, Ireland. sheillg@tcd.ie.
Sophie GrehanTrinity St James's Cancer Institute, Dublin, Ireland.
Annemarie E BennettUniversity of Dublin, Trinity College Dublin, Dublin, Ireland.
Conor BoweTrinity St James's Cancer Institute, Dublin, Ireland.
Julie BroderickUniversity of Dublin, Trinity College Dublin, Dublin, Ireland.
Kelly CoghlanTrinity St James's Cancer Institute, Dublin, Ireland.
Julie ReganUniversity of Dublin, Trinity College Dublin, Dublin, Ireland.
Juliette HusseyUniversity of Dublin, Trinity College Dublin, Dublin, Ireland.
John Ed O ConnellTrinity St James's Cancer Institute, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the feasibility and acceptability of a multi-modal exercise and education rehabilitation programme for patients post head and neck cancer (HNC) treatment.

methodsThis single-arm prospective feasibility study included patients in the first 2 years following treatment for HNC. Participants completed a 10-week multi-modal exercise and education programme including twice weekly online or in-person group exercise sessions and four education sessions. Feasibility was evaluated via recruitment, adherence, and compliance to the programme. Secondary outcomes examined physical function and quality of life. The acceptability of the programme was assessed through participant feedback.

resultsIn total, 22 participants were recruited (36% (n = 8) female, mean age 65.23 years (SD 14.53, range 27-87 years)). The recruitment rate was 24%. Most participants had a history of surgery including neck dissection (95.5%, n = 21) and seven had flap reconstruction (31.8%). Approximately 54.5% (n = 12) of the participants screened positively for lymphoedema. Five people engaged with classes online (average 16.25 classes, range 6-24). Most participants attended the in-person class (n = 14, average 9.86 classes range 1-20). One person chose to do online and in-person classes. Two participants enrolled in the online programme did not engage with the intervention. Measures of physical activity levels, strength, frailty, and physical well-being all increased significantly post intervention. Participants provided positive feedback on the programme, particularly valuing the social experience of exercising alongside peers with similar cancer experiences.

conclusionsThe intervention appears feasible in a group of complex cancer survivors of HNC, with a preference for in-person exercise classes. CLINICALTRIALS: GOV REGISTRATION NUMBER: NCT06646861.

Indexed as

Exercise TherapyHead and Neck NeoplasmsPatient Education as TopicQuality of LifeAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansMaleMiddle AgedPatient ComplianceProspective StudiesCancer rehabilitationFeasibilityHead and neck cancerPhysiotherapy

Identifiers

PMID42240720
PMCPMC13236784

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.