Evidence map›Paper›PMID 42240697›Full record

ReviewActa neurochirurgica2026

Dangers of orbital retraction in transorbital neuroendoscopic surgery.

Ayushi Agarwal, Jessica Y Tong, Dinesh Selva

Abstract readReview
In one paragraph

Review in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ayushi AgarwalSouth Australian Institute of Ophthalmology, The Royal Adelaide Hospital, Adelaide, Australia.ORCID 0000-0002-0635-3275
Jessica Y TongSydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. jessica.tong@adelaide.edu.au.
Dinesh SelvaSouth Australian Institute of Ophthalmology, The Royal Adelaide Hospital, Adelaide, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis review summarizes the risks associated with orbital retraction in transorbital neuroendoscopic surgery (TONES) and proposes practical strategies to optimize surgical freedom while preserving visual function.

methodsA qualitative review synthesized through a systematic literature search of PubMed (MEDLINE) database. Studies involving human or cadaveric TONES and endoscopic transorbital approaches were reviewed.

resultsTen studies met inclusion criteria, comprising cadaveric as well as human subjects. Virtual-reality and cadaveric models revealed that 10-11 mm of globe displacement provides adequate surgical freedom, whereas sustained retraction beyond approximately 15 mm results in steep rises in intraocular and intra-orbital pressure posing a higher risk of orbital compartment syndrome. Clinical reports link prolonged retraction to transient or permanent mydriasis, ocular hypotony, decompression retinopathy, and visual loss.

conclusionOrbital retraction is central to TONES but is the principal driver of ocular morbidity. Based on the available evidence, retraction should be dynamic, gentle, and intermittent, with globe displacement generally limited to 10-12 mm. Apex-directed focal pressure should be avoided, and continuous monitoring of pupil and intraocular pressure is essential. Multidisciplinary protocols are recommended to standardize safe retraction practices while preserving the advantages of TONES.

Indexed as

Intraoperative ComplicationsNeuroendoscopyOrbitOrbital DiseasesPostoperative ComplicationsHumansGlobe retractionOrbital compartment syndromeOrbital retractionSurgical freedomTransorbital neuroendoscopic surgery

Identifiers

PMID42240697
PMCPMC13427981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.