ArticleActa neurochirurgica2026
Technique and device specific diffusion-weighted imaging detected ischemic lesions and occlusion outcomes in endovascular treatment of unruptured aneurysms.
Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis prospective study evaluated 6-month aneurysm occlusion and diffusion-weighted imaging (DWI) lesion rates following endovascular treatment of unruptured intracranial aneurysms (UIAs). We hypothesized that complex techniques would yield better occlusion but more DWI lesions.
methodsWe conducted a single-center, prospective cohort study of consecutive patients treated for UIAs with 6-month angiographic follow-up. Treatment technique was categorized as complex (flow diversion, stent-assisted coiling [SAC], or balloon-assisted coiling [BAC]) or non-complex (simple coiling, Trenza-assisted coiling, or intrasaccular device placement). Aneurysm morphology was classified as complex and non-complex according to a Delphi statement. Primary outcomes were adequate occlusion (complete or neck residual) at 6 months and postprocedural DWI lesions, assessed by MRI.
resultsIn 113 patients, complex treatment was used in 96% (n = 25/26) of complex aneurysms, whereas 57% (n = 53/93) of non-complex aneurysms underwent non-complex treatment (p < 0.001). There were no differences in occlusion rates (90% vs. 81%, p = 0.181) or DWI rates (56% vs. 69%, p = 0.124) between non-complex and complex treatments. Aneurysm complexity associated with lower occlusion rates (67% vs. 90%, p = 0.012) but not with DWI lesion rates (58% vs. 65%, p = 0.524). Notably, individual techniques demonstrated greater variation in DWI rates (42-100%) than in occlusion rates (70-100%).
conclusionOcclusion rates at 6 months were high across techniques, but DWI lesion rates varied substantially between individual techniques. The ischemic burden appears to be driven by the specific endovascular technique rather than by broad categorizations of procedural complexity. Thus, careful technique selection is critical to minimize ischemic risk while appropriately addressing aneurysm complexity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.