Evidence map›Paper›PMID 42240465›Full record

ArticleJournal of studies on alcohol and drugs2026

Predictors of Follow-Up Engagement in an Adolescent Alcohol Longitudinal Cohort.

Tommy Gunawan, Ty Brumback, Michael L Thomas, Laika Aguinaldo, Daniel Lopez, Luis F S Castro-de-Araujo, Herry Patel, Emily Schulze, Sonja C Eberson, Mary J Meloy and 7 more

Abstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tommy GunawanDepartment of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, US; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, US.
Ty BrumbackXavier University, 3800 Victory Parkway, Cincinnati, OH 45207.
Michael L ThomasColorado State University, 1876 Campus Delivery, Fort Collins, CO 80523-1876 USA.
Laika AguinaldoUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Daniel LopezDepartment of Psychiatry, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 USA.
Luis F S Castro-de-AraujoVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 1 156, P.O. Box 980126, Richmond, VA, 23298-0126, USA; Department of Psychiatry, Austin Health, The University of Melbourne, Melbourne, VIC, Australia.
Herry PatelUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Emily SchulzeUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Sonja C EbersonUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Mary J MeloyUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Duncan B ClarkUniversity of Pittsburgh, 3811 O'Hara St., Pittsburgh, PA 15213 USA.
David B GoldstonDuke University, 2608 Erwin Road, Durham, NC 27705 USA.
Kate B NoonerUniversity of North Carolina Wilmington, College of Science & Engineering, 601 South College Road, Wilmington, NC 28409 USA.
Sandra A BrownUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Susan F TapertUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.
Vijay A RamchandaniHuman Psychopharmacology Laboratory, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892 USA.
Alejandro D MerueloUniversity of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA.

Funding

Alcohol Pharmacokinetics and Pharmacodynamics in HumansZIAAA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2009 to 2025
$31.2M
Sex Differences in Autonomic Nervous System Function and Depression Across AdolescenceU01AA021696 · NIAAA · SRI INTERNATIONAL · PI Fiona C Baker · 2012 to 2026
$12.2M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: San DiegoU01AA021692 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Susan F. Tapert · 2012 to 2026
$11.8M
NCANDA Research Project Site: DukeU01AA021681 · NIAAA · DUKE UNIVERSITY · PI DAVID B. GOLDSTON · 2012 to 2026
$9.8M
The TEEN Study: The Impact of Adolescent Drinking on Connectivity in the BrainU01AA021691 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Angelica Marie Morales, Bonnie J. Nagel · 2012 to 2026
$8.5M
NCANDA Research Project Site: University of Pittsburgh (NCANDA-PITT)U01AA021690 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN B. CLARK, BEATRIZ LUNA · 2012 to 2026
$7.6M
N-CANDA: DATA ANALYSIS COMPONENTU01AA021697 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, POHL, KILIAN MARIA · 2012 to 2015
$3.6M
Interpretable Deep Forecasting of Hazardous Substance Use during High SchoolR01DA057567 · NIDA · STANFORD UNIVERSITY · PI Kilian Maria Pohl, Susan F. Tapert · 2022 to 2026
$2.3M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: AdminU01AA021695 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, SANDRA A, TAPERT, SUSAN F · 2012 to 2015
$2.1M
Adolescent Markers of Depression and the Impact of Alcohol UseK23AA026869 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MERUELO, ALEJANDRO DANIEL · 2019 to 2023
$1.0M
Intramural NIH HHS ZIA AA000466NIAAA NIH HHS K23 AA026869NIAAA NIH HHS U01 AA021681NIAAA NIH HHS U01 AA021690NIAAA NIH HHS U01 AA021691NIAAA NIH HHS U01 AA021692NIAAA NIH HHS U01 AA021695NIAAA NIH HHS U01 AA021696NIAAA NIH HHS U01 AA021697NIDA NIH HHS R01 DA057567
6 · The paper itself

Abstract

objectiveAttrition can bias longitudinal findings, including those on alcohol use. We examined predictors of follow-up engagement in a multi-site neuroimaging cohort of youth.

methodData were drawn from the first nine annual waves of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA), which recruited 831 participants aged 12-21 years in 2013-2014 (52% female). Follow-up engagement was modeled as the total number of completed follow-up visits (0-9, excluding baseline) using Poisson regression with multiple imputation and family-cluster-robust standard errors. Secondary analyses examined categorical engagement levels. Primary predictors included exceeding age- and sex-specific baseline alcohol use thresholds, externalizing symptoms, race, and demographic and family factors.

resultsOverall engagement was high, with participants completing an average of approximately 9 of 10 possible visits. In Poisson models, exceeding baseline alcohol use thresholds was associated with a modest reduction in follow-up visits, although this did not reach statistical significance (IRR = 0.940, 95% CI: 0.881-1.004, p = .064). Externalizing symptoms were not significantly associated with engagement (IRR = 1.001, 95% CI: 0.998-1.003, p = .647). Sibling co-enrollment was associated with greater engagement (IRR = 1.058, 95% CI: 1.021-1.097, p = .002), while other factors showed small or non-significant associations.

conclusionsFollow-up engagement was generally high across adolescence into young adulthood. Exceeding baseline alcohol use thresholds showed a modest association with reduced engagement, although not statistically significant in the count model. Externalizing symptoms were not associated with engagement. Categorical analyses suggested a stronger association between exceeding baseline alcohol use thresholds and lower engagement groups. These findings may help identify participants who could benefit from additional engagement efforts.

Indexed as

Alcohol useEngagementLongitudinal cohortRetention strategiesSibling enrollmentYouth behavior

Identifiers

PMID42240465
PMCPMC13339738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.