ArticleAntimicrobial agents and chemotherapy2026
Does early letermovir initiation delay engraftment?
Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
Although letermovir prophylaxis has drastically reduced cytomegalovirus (CMV) infections in allogeneic hematopoietic cell transplantation recipients (allo-HCTR), the broader impact of letermovir prophylaxis remains unclear. We retrospectively analyzed hematological outcomes in CMV-seropositive allo-HCTR (R+) from the pre- and letermovir periods. Among 314 consecutive allo-HCTR+, engraftment was significantly delayed in allo-HCTR+ in the letermovir period, even after removing potential confounders, and despite improved survival. Similar trends were found after reviewing the literature, and this observation should raise vigilance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.