Evidence map›Paper›PMID 42240371›Full record

ArticleApplied and environmental microbiology2026

Strong mucosal adhesion enhances the anti-infective effectiveness of T4-like phages.

Shujie Luo, Bei Zhou, Hauke Smidt, Yan Lin, Weiyun Zhu

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shujie LuoLaboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.ORCID 0009-0009-5842-9794
Bei ZhouLaboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Hauke SmidtLaboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.ORCID 0000-0002-6138-5026
Yan LinLaboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0003-4196-3092
Weiyun ZhuLaboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0001-9222-6581

Funding

National Natural Science Foundation of China 31802102
6 · The paper itself

Abstract

Bacteriophage adhesion to intestinal mucus has been proposed as an important mechanism for preventing bacterial infection. However, whether differences in adhesion capacity among closely related phages translate into distinct protective outcomes remains unclear. In this study, we compared two T4-like bacteriophages, S143_2 and W143, to investigate how variation in mucosal adhesion influences antibacterial efficacy and host responses. Both phages exhibited comparable lytic activity against enteropathogenic

Indexed as

Bacteriophage T4Enteropathogenic Escherichia coliEscherichia coli InfectionsIntestinal MucosaVirus AttachmentAnimalsCell LineFemaleMiceimmune responsephage adherencephage therapyprotective efficacy

Identifiers

PMID42240371
PMCPMC13390416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.