ArticleTranslational vision science & technology2026
Age Modifies the Comparative Effectiveness of DIMS Versus HAL Spectacle Lenses for Myopia Control: A Real-World Study.
Article in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comparison of effectiveness of four myopia control interventions in Chinese children: a real-world retrospective study.Eye and vision (London, England) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To compare the real-world myopia control effectiveness of defocus incorporated multiple segments (DIMS) versus highly aspherical lenslets (HAL) spectacle lenses in children, and assess effect modification by age, baseline refraction, and axial length (AL). Methods: This retrospective cohort study included 180 children (aged 6 to 14) wearing DIMS or HAL lenses for ≥12 months. Participants were stratified by baseline spherical equivalent (SER) into pre-myopia, low myopia, and moderate myopia subgroups. Annual AL and SER changes were analyzed using analysis of covariance, with interaction terms tested for effect modification. Results: After adjustment, the HAL group showed significantly slower annual axial elongation (adjusted mean difference = 0.08 mm; 95% confidence interval [CI], 0.03 to 0.12; P < 0.001) and SER progression (-0.14 D; 95% CI, -0.25 to -0.03; P = 0.012) compared to DIMS. A significant treatment-by-age interaction was observed for AL change (P = 0.024). HAL's advantage was pronounced in younger children (≤10.5 years; AL difference = 0.13 mm; P < 0.001) but not significant in older children. Categorically, HAL yielded a higher proportion of "good" AL responders (64.4% vs. 41.1%; P = 0.004), most notably in pre-myopia. Axial shortening was observed exclusively in HAL wearers (8.9%). Conclusions: Over one year, HAL lenses demonstrated superior myopia control efficacy versus DIMS in a real-world setting. Age was a key effect modifier, with greater benefit in younger children, supporting age-stratified clinical decision-making. Translational Relevance: This study identifies patient age as a key biological modifier of the treatment response to different optical designs, bridging the mechanistic understanding of visual development with actionable, personalized clinical prescribing for childhood myopia control. 目的: (DIMS) (HAL) , 、 (AL) 。. 方法: 180 DIMS HAL ≥ 12 ( 6-14) 。 (SER) 、。 (ANCOVA) AL SER , 。. 结果: , DIMS , HAL (: 0.08 mm, 95% CI: 0.03 ∼ 0.12, P < 0.001), SER (-0.14 D, 95% CI: -0.25 ∼ -0.03, P = 0.012) 。 AL (P = 0.024) 。 HAL (≤10.5 ; AL : 0.13 mm, P < 0.001) , 。, HAL AL "" (64.4% vs. 41.1%, P = 0.004), 。 HAL (8.9%) 。. 结论: , HAL DIMS 。, , 。. 关键词: ; ; ;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.