ArticleSmall (Weinheim an der Bergstrasse, Germany)2026
Engineering a High-Affinity Monoclonal Antibody for Thiram Immunoassays and Protection.
Linfang Lu, Kang Jiang, Na Li, Xiaoli Li, Lakshani Madushika, Sumei Ling, Shihua Wang
Abstract read
In one paragraphArticle in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Linfang LuThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.ORCID https://orcid.org/0009-0001-6640-8282 Kang JiangThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Na LiThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Xiaoli LiThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Lakshani MadushikaThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Sumei LingThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.ORCID https://orcid.org/0000-0002-0812-0037 Shihua WangThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, Fujian Key Laboratory of Pathogenic Fungi and Mycotoxins, School of Life Sciences, and School of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Funding
Instrumental Analysis Center of Fujian Agriculture and Forestry UniversityNational Key Research and Development Program of China 2023YFD1600503Promotion of Marine and fishery industries projects in Fujian Province FJHYF-L-2023-21
6 · The paper itselfAbstract
Thiram (TMTD), a widely used dithiocarbamate fungicide, provokes oxidative hepatotoxicity, yet practical strategies for its detection and immunoprotection remain scarce. Here we develop an antibody-enabled framework integrating detection, therapy, and prevention against TMTD. In the murine model, we characterized the dose-dependent hepatic injury induced by TMTD. Guided by rational C
Indexed as
Antibodies, MonoclonalAntibody AffinityThiramAnimalsImmunoassayLiverMiceAntibodies, MonoclonalThiramimmunoprotectionMOF‐based immunoassaymonoclonal antibodythiram
Identifiers
PMID42240039
PMCPMC13392691
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