ReviewUnited European gastroenterology journal2026
Potential of Clinical Care-Collected Gut Biopsies for Advancing Personalised Medicine in Inflammatory Bowel Disease.
Review in United European gastroenterology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
Abstract
The management of inflammatory bowel disease (IBD) is challenged by significant patient diversity and a lack of effective profiling tools. This review evaluates the potential of archived formalin-fixed, paraffin-embedded (FFPE) gut biopsies as a resource for translational and precision medicine, given their global availability and associated long-term clinical data. Recent technical advances have expanded the molecular toolbox for FFPE samples to include proteomics, metabolomics, glycomics, spatial transcriptomics and characterising microbial components via 16S rRNA sequencing. Despite their potential, the use of FFPE materials is hindered using heterogeneous collection and storage methods. Consequently, the authors recommend implementing standardised guideline protocols for routine IBD biopsy management to facilitate high-quality research, improve disease understanding and support the identification of clinically translatable biomarkers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.