Evidence map›Paper›PMID 42239958›Full record

ReviewFrontiers in medicine2026

The role of acupuncture as a complementary therapy for sepsis: a narrative review of the evidence and future trial directions.

Li-Yuan Zhuo, Xin Bao, Ming-Xi Lai, M Adeel Alam Shah, Xiao-Feng Chen, Shan Jiang, Zhen-Yang Wei, Rong-Lin Chen, Shan-Qiang Zhang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li-Yuan Zhuo *Department of Critical Care Medicine, Longgang Central Hospital, Shantou University Medical College, Shenzhen, China.
Xin Bao *Department of Pathology, Longgang Central Hospital, Shantou University Medical College, Shenzhen, China.
Ming-Xi LaiDepartment of Internal Medicine, Baoan Maternal and Child Health Hospital, Shenzhen, China.
M Adeel Alam ShahDepartment of Anatomy, Shantou University Medical College, Shantou, China.
Xiao-Feng ChenDepartment of Burn Unit, Longgang Central Hospital, Shantou University Medical College, Shenzhen, China.
Shan JiangDepartment of Critical Care Medicine, Longgang Central Hospital, Shantou University Medical College, Shenzhen, China.
Zhen-Yang WeiDepartment of Anatomy, Shantou University Medical College, Shantou, China.
Rong-Lin ChenDepartment of Critical Care Medicine, Longgang Central Hospital, Shantou University Medical College, Shenzhen, China.
Shan-Qiang ZhangDepartment of Anatomy, Shantou University Medical College, Shantou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Current interventions are insufficient to halt rising morbidity and mortality, prompting interest in complementary therapies including acupuncture. This narrative review systematically searched clinical studies published from 2010 to 2026 evaluating acupuncture as a complementary therapy for sepsis. Seventeen studies met inclusion criteria. We analyzed study design, participant characteristics, intervention modalities, acupoint selection, outcome measures, and safety, and explored connections between traditional Chinese medicine and modern biomedical mechanisms. The available evidence is insufficient to recommend routine acupuncture use for sepsis. High-quality trials are needed, adhering to Standard for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) and Consolidated Standards of Reporting Trials (CONSORT) guidelines, and using the Oxford Center for Evidence-Based Medicine Level of Evidence Scale to screen optimal acupoint combinations. This review synthesizes existing clinical evidence and provides a rigorous reference for designing future trials.

Indexed as

acupunctureclinical trialmeridiansepsistraditional Chinese medicine

Identifiers

PMID42239958
PMCPMC13226545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.