Evidence map›Paper›PMID 42239846›Full record

ArticleThe Journal of clinical and aesthetic dermatology2026

An Analysis of Thyrotropin Levels in Patients With Nonscarring Alopecia: A Single-Center Retrospective Comparative Study.

Simona A Alomary, Nicole J Baker, Nicholas Schell, Temitayo Ogunleye, Susan Taylor, Heather Milbar

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Article in The Journal of clinical and aesthetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Simona A AlomaryMs. Alomary is with Rutgers New Jersey Medical School, Newark, New Jersey, and Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.
Nicole J BakerMs. Baker is with Sidney Kimmel Medical College at Thomas Jefferson University and the University of Pennsylvania Perelman School of Medicine, Department of Dermatology, Philadelphia, Pennsylvania.
Nicholas SchellMr. Schell and Drs. Ogunleye, Taylor, and Milbar are with the University of Pennsylvania Perelman School of Medicine, Department of Dermatology, Philadelphia, Pennsylvania.
Temitayo OgunleyeMr. Schell and Drs. Ogunleye, Taylor, and Milbar are with the University of Pennsylvania Perelman School of Medicine, Department of Dermatology, Philadelphia, Pennsylvania.
Susan TaylorMr. Schell and Drs. Ogunleye, Taylor, and Milbar are with the University of Pennsylvania Perelman School of Medicine, Department of Dermatology, Philadelphia, Pennsylvania.
Heather MilbarMr. Schell and Drs. Ogunleye, Taylor, and Milbar are with the University of Pennsylvania Perelman School of Medicine, Department of Dermatology, Philadelphia, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare thyrotropin (TSH) levels across nonscarring alopecia (NSA) subtypes-alopecia areata (AA), telogen effluvium (TE), and androgenetic alopecia (AGA)-in a primary analysis of all patients, a secondary analysis of euthyroid patients stratified into low-normal (0.5-2.5 mIU/L) and high-normal (2.5-4.5 mIU/L) categories, and a tertiary analysis of patients with thyroid dysfunction.

methodsA retrospective chart review was conducted on patients diagnosed with AA, TE, or AGA at a single academic dermatology department between August 2017 and August 2024. TSH values were drawn within 3 months of the initial visit, and patient demographics were extracted from the electronic medical record. Patients with thyroid dysfunction were excluded from the secondary analysis. TSH values within the euthyroid range were stratified into low-normal and high-normal categories. A tertiary analysis of patients with frank thyroid dysfunction was later conducted. Descriptive statistics, Kruskal-Wallis tests, and Bonferroni-corrected pairwise comparisons were performed.

resultsAmong the 1,411 patients initially identified, most TSH values were within the euthyroid range. In a secondary analysis of 1,291 euthyroid patients, there was no significant difference in TSH distribution across NSA subtypes, including when stratified into low-normal vs high-normal categories. Among patients with thyroid dysfunction (8.5%), those with TE had the highest relative proportions of both hypothyroidism (5.0%) and hyperthyroidism (5.5%). Black or African American patients with AA and TE had lower mean TSH levels than White patients; however, this was not observed in AGA. LIMITATIONS: Limitations of this study include the retrospective design and the potential for incomplete or biased medical records.

conclusionTSH levels among patients with NSA did not vary significantly based on NSA subtype. Racial differences in mean TSH were observed in AA and TE, but the clinical significance remains uncertain.

Indexed as

alopecia areataandrogenetic alopecianonscarring alopeciatelogen effluviumTSH

Identifiers

PMID42239846
PMCPMC13229151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.