Evidence map›Paper›PMID 42239646›Full record

ArticleFrontiers in cellular neuroscience2026

Histone demethylase KDM6B promotes postnatal oligodendrocyte maturation and cortical myelination.

Ruth Lambries, Zihan Shen, George I Mias, Jin He

Abstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ruth Lambries *Department of Biochemistry and Molecular Biology, College of Natural Science, Michigan State University, East Lansing, MI, United States.
Zihan Shen *Department of Biochemistry and Molecular Biology, College of Natural Science, Michigan State University, East Lansing, MI, United States.
George I MiasDepartment of Biochemistry and Molecular Biology, College of Natural Science, Michigan State University, East Lansing, MI, United States.
Jin HeDepartment of Biochemistry and Molecular Biology, College of Natural Science, Michigan State University, East Lansing, MI, United States.

Funding

Epigenetic mechanisms of Ash1L in transcriptional activationR01GM127431 · NIGMS · MICHIGAN STATE UNIVERSITY · PI HE, JIN · 2018 to 2022
$1.7M
Epigenetic mechanisms of histone methyltransferase ASH1L in autism spectrum disorderR01MH130544 · NIMH · MICHIGAN STATE UNIVERSITY · PI HE, JIN · 2023 to 2025
$1.5M
NIGMS NIH HHS R01 GM127431NIMH NIH HHS R01 MH130544
6 · The paper itself

Abstract

Introduction: Postnatal cortical myelination requires epigenetic activation of oligodendrocyte gene programs, but the role of histone demethylases Methods: We conditionally deleted Results: Discussion: These findings define a KDM6B→

Indexed as

histone demethylaseKDM6Bmyelinationneurodevelopmentoligodendrocyte

Identifiers

PMID42239646
PMCPMC13225964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.