Repeatability of focal changes in knee cartilage T

Kaitlin G Sofko, Ibukunoluwa O Elebute, Lumeng Cui, Natasha M Bzowey, Marianne S Black, Emily J McWalter

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Article in Osteoarthritis imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kaitlin G SofkoDepartment of Mechanical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK, S7N 5B2, Canada.

Ibukunoluwa O ElebuteDepartment of Mechanical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK, S7N 5B2, Canada.

Lumeng CuiDepartment of Biomedical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK S7N 5B2, Canada.

Natasha M BzoweyDepartment of Mechanical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK, S7N 5B2, Canada.

Marianne S BlackDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall - Building 530, Stanford, CA, 94305, USA.

Emily J McWalterDepartment of Mechanical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK, S7N 5B2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study is to assess the repeatability of focal changes in T Design: A short-term repeatability study was conducted in five healthy participants. Images were acquired of the knee in an unloaded position and in loaded flexion with a custom, quantitative Double Echo Steady State (qDESS) MRI sequence on a 3T scanner. The protocol was carried out three times within a one-week period. T Results: The SDrms of the percentage area of the entire cartilage surface covered by clusters when the knees were loaded was <9.5 %. The repeatability of the percentage area of the entire cartilage surface covered by clusters over time was <4.5 % for the unloaded knees and 7.4 % for the loaded knees. For the regional analysis, the average SDrms of the entire plate was <3.0 ms. Conclusion: Cluster analysis provides important information on focal changes in cartilage with the application of load and over time, but at the cost of repeatability compared to regional approaches.

Indexed as

CartilageKneeLoadingRepeatabilityT2 Relaxation Time MRI

Identifiers

PMID42239632

DOI10.1016/j.ostima.2025.100384

PMCPMC13228706

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.