ArticleFrontiers in cellular and infection microbiology2026
Towards new care strategies in a suburban healthcare center in La Matanza, Argentina: performance evaluation of rapid diagnostic tests for Chagas disease in a non-endemic area.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Chagas disease, caused by the protozoan parasite Methods: We aimed to characterize the clinical, parasitological, and sociodemographic profile of individuals with Results: In this cross-sectional prospective study including 103 subjects, epidemiological analysis revealed that most infected individuals originated from endemic areas, with a substantial proportion of infections consistent with congenital transmission. Clinical evaluation identified electrocardiographic abnormalities in 30.9 % of infected patients, predominantly right bundle branch block. Molecular characterization showed parasites belonging to DTU V (Discrete Typing Unit V) in 7 infections (one coinfected with DTU VI). RDT1 showed a sensitivity of 82.5 % and specificity of 100 %, whereas RDT2 exhibited a sensitivity of 87.5 % and specificity of 85.7 %. Discussion: Overall, our findings provide a comprehensive characterization of
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