Evidence map›Paper›PMID 42239438›Full record

ArticlebioRxiv : the preprint server for biology2026

Visual exoproteomics of

Matthew P Agdanowski, Matthew J Kensil, Trevor H Moser, Ethan Humm, Yaneli I Guandique, Kayleigh Mason-Chalmers, Tracy Al-Set, Rachel R Ogorzalek Loo, James E Evans, Robert P Gunsalus and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matthew P AgdanowskiDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Matthew J KensilDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Trevor H MoserEnvironmental Molecular Sciences Laboratory (EMSL); Pacific Northwest National Laboratory, Richland, WA 99354, USA.
Ethan HummDepartment of Microbiology Immunology and Molecular Genetics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Yaneli I GuandiqueDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Kayleigh Mason-ChalmersDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Tracy Al-SetDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Rachel R Ogorzalek LooDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
James E EvansEnvironmental Molecular Sciences Laboratory (EMSL); Pacific Northwest National Laboratory, Richland, WA 99354, USA.
Robert P GunsalusDepartment of Microbiology Immunology and Molecular Genetics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Joseph A LooDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0001-9989-1437
Jose A RodriguezDepartment of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0002-0248-4964

Funding

Micro Electron Diffraction of Toxic and/or Infectious Macromolecular NanoassembliesR35GM128867 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jose Alfonso Rodriguez · 2018 to 2026
$3.1M
A Mid-Level 200kV Instrument for Single-Particle cryoEMS10OD032459 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2022 to 2022
$2.0M
Advancing Mass Spectrometry Analyses of Proteins, Assemblies, and ProteoformsR35GM145286 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Joseph A Loo · 2022 to 2026
$1.9M
NIGMS NIH HHS R35 GM128867NIGMS NIH HHS R35 GM145286NIH HHS S10 OD032459
6 · The paper itself

Abstract

Visual proteomics enables the study of low-abundance proteins and identification of unknown complexes from heterogeneous samples by complementing high-resolution cryogenic electron microscopy (cryoEM) with external inputs on protein identity such as mass spectrometry. Using this approach, we interrogated the exoproteome of the anaerobic cellulose-degrading bacterium

Indexed as

biomass degradationcellulosecryoEMvisual proteomics

Identifiers

PMID42239438
PMCPMC13228470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.