Evidence map›Paper›PMID 42239382›Full record

ArticlebioRxiv : the preprint server for biology2026

Regulation of the histone H3K36 methyltransferase Set2 by the histone chaperone Spt6.

Alexandra R Elchert, Vanda Lux, James L Warner, Tereza Nešporová, Václav Veverka, Fred Winston

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alexandra R ElchertDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-7669-5468
Vanda LuxInstitute of Organic Chemistry and Biochemistry of the CAS, Prague 16000, Czech Republic.ORCID 0000-0002-0184-8076
James L WarnerDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115 USA.ORCID 0000-0002-7960-7360
Tereza NešporováInstitute of Organic Chemistry and Biochemistry of the CAS, Prague 16000, Czech Republic.
Václav VeverkaInstitute of Organic Chemistry and Biochemistry of the CAS, Prague 16000, Czech Republic.ORCID 0000-0003-3782-5279
Fred WinstonDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-4759-5537

Funding

Analysis of conserved eukaryotic transcription elongation factorsR01GM135251 · NIGMS · HARVARD MEDICAL SCHOOL · PI WINSTON, FRED M. · 2021 to 2024
$1.7M
NIGMS NIH HHS R01 GM135251
6 · The paper itself

Abstract

Histone H3 lysine 36 methylation is a conserved histone modification that is critical for maintaining eukaryotic transcriptional fidelity and genomic stability. In

Identifiers

PMID42239382
PMCPMC13228609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.