Evidence map›Paper›PMID 42239380›Full record

ArticlebioRxiv : the preprint server for biology2026

Ventral Pallidum Cholinergic Neurons Respond to Reward and Signal Reward Value.

Alexander Gannon, Ruby Setara, Czarina M Maysonet, Ronald E Salazar, Dustin R Zuelke, Jane E Bowen, Eduardo F Gallo

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander GannonDepartment of Biological Sciences, Fordham University, Bronx, NY.
Ruby SetaraDepartment of Biological Sciences, Fordham University, Bronx, NY.
Czarina M MaysonetDepartment of Biological Sciences, Fordham University, Bronx, NY.
Ronald E SalazarDepartment of Biological Sciences, Fordham University, Bronx, NY.
Dustin R ZuelkeDepartment of Biological Sciences, Fordham University, Bronx, NY.
Jane E BowenDepartment of Biological Sciences, Fordham University, Bronx, NY.
Eduardo F GalloDepartment of Biological Sciences, Fordham University, Bronx, NY.ORCID 0000-0001-9906-1425

Funding

Cholinergic interneuron D2 receptor function in impulsive behavior: implications for addictionR01DA055018 · NIDA · FORDHAM UNIVERSITY · PI Eduardo Francisco Gallo · 2022 to 2026
$2.0M
NIDA NIH HHS R01 DA055018
6 · The paper itself

Abstract

The ventral pallidum (VP) is a key basal ganglia structure involved in integrating reward-related signals to guide motivated behavior and feeding. VP neuronal activity is strongly tuned to reward-predictive cues and palatable rewards, tracking changes in value and motivational state. Recent studies have established important and opposing roles for GABAergic and glutamatergic VP neurons in reward- and avoidance-related behaviors. However, much less is known about the role of VP cholinergic neurons (VP-CNs), which comprise only ~10% of VP neurons in mice, but maintain extensive connectivity with reward-related circuitry. Here, using cell type-selective

Identifiers

PMID42239380
PMCPMC13228558

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.