Evidence map›Paper›PMID 42239373›Full record

ArticlebioRxiv : the preprint server for biology2026

The

Kaleb Boswinkle, Paige N Roehling, Jasmine Narakorn, Thomas Carell, Agnieszka Dziergowska, Patricia C Dos Santos, Jeffrey S Mugridge, Valérie de Crécy-Lagard

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaleb BoswinkleDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611.
Paige N RoehlingDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE, 19716, USA.
Jasmine NarakornDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611.
Thomas CarellCenter for Nucleic Acid Therapeutics at the Department of Chemistry, Institute for Chemical Epigenetics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, München, Germany.
Agnieszka DziergowskaInstitute of Organic Chemistry, Lodz University of Technology, Łódź, Poland.
Patricia C Dos SantosDepartment of Chemistry, Wake Forest University, Winston-Salem, NC, 27101, USA.ORCID 0000-0002-3364-0931
Jeffrey S MugridgeDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE, 19716, USA.ORCID 0000-0002-1553-3008
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611.ORCID 0000-0002-9955-3785

Funding

Selectivity and regulation of mRNA demethylation by iron-dependent dioxygenasesR35GM143000 · NIGMS · UNIVERSITY OF DELAWARE · PI MUGRIDGE, JEFFREY SCOTT · 2021 to 2025
$2.1M
Linking gene and function through comparative genomic and experimental approachesR35GM156215 · NIGMS · UNIVERSITY OF FLORIDA · PI Valerie A de Crecy-Lagard · 2025 to 2026
$1.3M
NIGMS NIH HHS R35 GM143000NIGMS NIH HHS R35 GM156215
6 · The paper itself

Abstract

tRNA wobble base uridines are heavily modified to influence anticodon:codon base pairing and tune the structure of the anticodon stem loop for efficient and accurate translation. Both Gram-positive and negative bacteria, as well as certain archaea, modify wobble uridines to contain either a 5-carboxymethylaminomethyl (cmnm

Indexed as

FAD-dependent oxidaseradical SAMtRNA modifications

Identifiers

PMID42239373
PMCPMC13228596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.