Evidence map›Paper›PMID 42239325›Full record

ArticlebioRxiv : the preprint server for biology2026

TSC2 is a stress granule suppressor.

Yizhe Ma, Natalie G Farny

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yizhe MaDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.ORCID 0000-0003-4556-2878
Natalie G FarnyDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.ORCID 0000-0003-1143-4560

Funding

Structure, Function, and Dynamics of Non-Canonical Stress GranulesR15GM157697 · NIGMS · WORCESTER POLYTECHNIC INSTITUTE · PI FARNY, NATALIE GILKS · 2025 to 2025
$446k
Identification of Genetic Suppressors of RNA GranulesR03AG077140 · NIA · WORCESTER POLYTECHNIC INSTITUTE · PI FARNY, NATALIE GILKS · 2022 to 2023
$147k
NIA NIH HHS R03 AG077140NIGMS NIH HHS R15 GM157697
6 · The paper itself

Abstract

Stress granules (SGs) are dynamic, membrane-less ribonucleoprotein assemblies that form through liquid-liquid phase separation to prioritize stress-survival proteostasis. Through reanalysis of a

Indexed as

RNAi screenStress granulestranslational controltuberous sclerosis complex

Identifiers

PMID42239325
PMCPMC13228204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.