Evidence map›Paper›PMID 42239240›Full record

ArticlebioRxiv : the preprint server for biology2026

Nuclear basket localized proteasomes maintain circadian period through nuclear TOC1 proteolysis.

Yeon Jeong Kim, Breagha Magill, Jing-Wen Yao, Hua Shi, Yun Sun Lee, Iris Meier, David E Somers

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yeon Jeong KimDepartment of Molecular Genetics, The Ohio State University, Columbus OH 43210 USA.
Breagha MagillDepartment of Molecular Genetics, The Ohio State University, Columbus OH 43210 USA.
Jing-Wen YaoDepartment of Molecular Genetics, The Ohio State University, Columbus OH 43210 USA.
Hua ShiState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming, 650201, China.
Yun Sun LeeCrop Biotechnology Institute, Institutes of Green-bio Science and Technology and Department of International Agricultural Technology Seoul National University, Pyeongchang, Republic of Korea.
Iris MeierDepartment of Molecular Genetics, The Ohio State University, Columbus OH 43210 USA.
David E SomersDepartment of Molecular Genetics, The Ohio State University, Columbus OH 43210 USA.ORCID 0000-0001-5170-2430

Funding

Post-translational control mechanisms of the circadian clockR01GM093285 · NIGMS · OHIO STATE UNIVERSITY · PI SOMERS, DAVID E · 2010 to 2018
$2.7M
Inter- and intracellular mechanisms of circadian regulationR35GM136400 · NIGMS · OHIO STATE UNIVERSITY · PI SOMERS, DAVID E · 2020 to 2024
$1.9M
NIGMS NIH HHS R01 GM093285NIGMS NIH HHS R35 GM136400
6 · The paper itself

Abstract

Post-translational control of circadian period can involve changes in protein intracellular localization to affect clock function. Many clock proteins rely on a nuclear presence for their activity. As the primary gateway regulating the movement of molecules between the cytosol and the nucleus, the nuclear pore may assist in circadian system maintenance. We describe roles for the nuclear basket proteins, NUA and NUP136, in the maintenance of

Identifiers

PMID42239240
PMCPMC13228199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.