Evidence map›Paper›PMID 42239227›Full record

ArticlebioRxiv : the preprint server for biology2026

The Prion-Like Properties of the INO80 Chromatin Remodeler Regulate Metabolic Gene Expression.

Dylan C Englund, Keith C Garcia, Daniel F Jarosz, Ashby J Morrison

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dylan C EnglundDepartment of Biology, Stanford University, Stanford, CA 94305, USA.
Keith C GarciaDepartment of Biology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-6078-5159
Daniel F JaroszDepartment of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-3497-5888
Ashby J MorrisonDepartment of Biology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-1228-5093

Funding

The Role of Chromatin in Metabolic Homeostasis SupplementalR35GM119580 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 2016 to 2025
$4.7M
Investigating protein phase separation and aggregation in age dependent human diseaseR01AG086495 · NIA · STANFORD UNIVERSITY · PI Daniel Jarosz · 2024 to 2026
$3.6M
NIA NIH HHS R01 AG086495NIGMS NIH HHS R35 GM119580
6 · The paper itself

Abstract

The INO80 chromatin-remodeling complex is a multi-subunit regulator of DNA-templated processes, yet the mechanisms that control remodeler function

Indexed as

aggregationArp5chromatinIes6INO80metabolismprionprotein disordertranscription

Identifiers

PMID42239227
PMCPMC13228451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.