Evidence map›Paper›PMID 42239140›Full record

ArticlebioRxiv : the preprint server for biology2026

NOD2 activation reprograms infiltrating inflammatory monocytes in the Zika virus infected CNS to maintain neural correlates of learning and memory.

Jeremy D Hill, Alice H W Dong, Joshua Liu, Marina Diniz Barbezani, Tallulah S Andrews, Robyn S Klein

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeremy D HillDepartment of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON.
Alice H W DongDepartment of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON.
Joshua LiuDepartment of Medicine, Washington University School of Medicine, St. Louis, MO.
Marina Diniz BarbezaniDepartment of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON.
Tallulah S AndrewsDepartment of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON.
Robyn S KleinDepartment of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON.ORCID 0009-0005-3876-8976

Funding

Viral and host factors in neuroinvasion of encephalitis alphavirusesR01AI160188 · NIAID · WASHINGTON UNIVERSITY · PI WILLIAM B KLIMSTRA, Robyn S. Klein · 2022 to 2026
$2.8M
NIAID NIH HHS R01 AI160188
6 · The paper itself

Abstract

Zika virus (ZIKV) encephalitis induces cytokine-mediated cognitive deficits which persist long-term. Here, we determined if NOD2-mediated conversion of monocytes from Ly6C

Indexed as

adult neurogenesisinflammatory monocytemicrogliamuramyl dipeptideNOD2spatial learning and memorysynapse eliminationViral encephalitisZika virus

Identifiers

PMID42239140
PMCPMC13228345

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.