Evidence map›Paper›PMID 42239123›Full record

ArticlebioRxiv : the preprint server for biology2026

BLOC1S1 regulates autolysosomal and exosomal dynamics during CD4

Rahul Sharma, Zulfeqhar A Syed, Sandeep K Vishwakarma, Kaiyuan Wu, Kim Han, Anand K Gupta, Christian A Combs, Michael N Sack

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rahul SharmaLaboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, Maryland, USA.
Zulfeqhar A SyedElectron Microscopy Core Facility, NHLBI, NIH, Bethesda, Maryland, USA.
Sandeep K VishwakarmaLaboratory of Retinal Cell and Molecular Biology, NEI, Maryland, USA.
Kaiyuan WuCardiovascular Branch, NHLBI, NIH, Bethesda, Maryland, USA.
Kim HanLaboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, Maryland, USA.
Anand K GuptaLaboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, Maryland, USA.
Christian A CombsLight Microscopy Core, NHLBI, NIH, Bethesda, Maryland, USA.
Michael N SackLaboratory of Mitochondrial Biology and Metabolism, NHLBI, NIH, Bethesda, Maryland, USA.ORCID 0000-0002-3411-0000

Funding

Mitochondrial biology in diabetesZIAHL005199 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2009 to 2025
$17.2M
Mitochondrial Biology in Cardiovascular DiseaseZ01HL005102 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2005 to 2008
$1.2M
Intramural NIH HHS Z01 HL005102Intramural NIH HHS ZIA HL005199
6 · The paper itself

Abstract

Although the endolysosome system is central to intracellular recycling, signal transduction, and intercellular communication

Indexed as

BLOC1S1CD4+ T cellscytokine secretionendolysosomal traffickingexosomesTh2 polarization

Identifiers

PMID42239123
PMCPMC13228349

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.