ArticlebioRxiv : the preprint server for biology2026
Establishment of a murine resident dermal macrophage cell line.
Stephanie L Brandt, Anderson Sá-Nunes, Ana C G Salina, Allison Judge, Dante Reyna, Amondrea Blackman, Nathan Klopfenstein, C Henrique Serezani
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Stephanie L BrandtDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Anderson Sá-NunesDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Ana C G SalinaDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Allison JudgeDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-4289-1748 Dante ReynaDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Amondrea BlackmanDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Nathan KlopfensteinDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
C Henrique SerezaniDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-5363-415X Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MNRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6MChemical Biology of Infectious Diseases (CBID) Training ProgramT32AI112541 · NIAID · VANDERBILT UNIVERSITY · PI Eric P Skaar · 2015 to 2026
$4.0MHyperglycemia and increased severity to Staphylococcus aureus infections.R01AI180777 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI C. Henrique Serezani · 2024 to 2026
$2.1MProstaglandin E2 Actions and Enhanced Susceptibility to Skin Infection in Diabetic MiceR01DK122147 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SEREZANI, C. HENRIQUE · 2020 to 2022
$1.7MNCATS NIH HHS TL1 TR002244NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI180777NIAID NIH HHS T32 AI112541NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK122147
6 · The paper itselfAbstract
Resident dermal macrophages (DMs) play essential roles in maintaining skin homeostasis and initiating inflammatory responses during tissue injury and against infectious agents. However, studies of their cellular mechanisms have been limited by their low abundance in steady-state skin and by technical challenges in isolating resident DMs. Here, we describe the generation and characterization of a novel DM cell line, termed SB89. F4/80
Indexed as
cell linecytokinesdermal macrophagesinnate immunityphagocytosisRNAiskin
Identifiers
PMID42239094
PMCPMC13228200
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