Evidence map›Paper›PMID 42239094›Full record

ArticlebioRxiv : the preprint server for biology2026

Establishment of a murine resident dermal macrophage cell line.

Stephanie L Brandt, Anderson Sá-Nunes, Ana C G Salina, Allison Judge, Dante Reyna, Amondrea Blackman, Nathan Klopfenstein, C Henrique Serezani

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie L BrandtDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Anderson Sá-NunesDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Ana C G SalinaDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Allison JudgeDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-4289-1748
Dante ReynaDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Amondrea BlackmanDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Nathan KlopfensteinDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
C Henrique SerezaniDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-5363-415X

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Chemical Biology of Infectious Diseases (CBID) Training ProgramT32AI112541 · NIAID · VANDERBILT UNIVERSITY · PI Eric P Skaar · 2015 to 2026
$4.0M
Hyperglycemia and increased severity to Staphylococcus aureus infections.R01AI180777 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI C. Henrique Serezani · 2024 to 2026
$2.1M
Prostaglandin E2 Actions and Enhanced Susceptibility to Skin Infection in Diabetic MiceR01DK122147 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SEREZANI, C. HENRIQUE · 2020 to 2022
$1.7M
NCATS NIH HHS TL1 TR002244NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI180777NIAID NIH HHS T32 AI112541NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK122147
6 · The paper itself

Abstract

Resident dermal macrophages (DMs) play essential roles in maintaining skin homeostasis and initiating inflammatory responses during tissue injury and against infectious agents. However, studies of their cellular mechanisms have been limited by their low abundance in steady-state skin and by technical challenges in isolating resident DMs. Here, we describe the generation and characterization of a novel DM cell line, termed SB89. F4/80

Indexed as

cell linecytokinesdermal macrophagesinnate immunityphagocytosisRNAiskin

Identifiers

PMID42239094
PMCPMC13228200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.