Evidence map›Paper›PMID 42239085›Full record

ArticlebioRxiv : the preprint server for biology2026

Discovery of a Novel Non-MET-Mediated Otoprotective Compound Against Aminoglycoside-Induced Ototoxicity.

Elizabeth Kara, Christopher Nicolet, Shaikh Emdadur Rahman, Travis Hudok, Caleb Leach, Kaden Falkner, Kenneth A Cornell, Dong Xu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth KaraDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, Idaho State University, Meridian, ID 83642, USA.
Christopher NicoletDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, Idaho State University, Meridian, ID 83642, USA.
Shaikh Emdadur RahmanDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, Idaho State University, Meridian, ID 83642, USA.
Travis HudokDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.
Caleb LeachDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.
Kaden FalknerDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.
Kenneth A CornellDepartment of Chemistry and Biochemistry, Boise State University, Boise, ID 83725, USA.
Dong XuDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, Idaho State University, Meridian, ID 83642, USA.ORCID 0000-0001-7056-2728

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Scott A Minnich · 2012 to 2026
$59.8M
Tracking and EvaluationU54GM104944 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI SY, FRANCISCO S · 2013 to 2023
$39.6M
Optimizing Deep Brain Stimulation for Parkinson's Disease.P20GM148321 · NIGMS · BOISE STATE UNIVERSITY · PI Javier Ochoa-Reparaz · 2023 to 2026
$10.2M
NIGMS NIH HHS P20 GM103408NIGMS NIH HHS P20 GM148321NIGMS NIH HHS U54 GM104944
6 · The paper itself

Abstract

Aminoglycoside (AG) antibiotics are indispensable for treating severe infections but frequently cause irreversible hearing loss, with no approved preventive therapies. Using

Identifiers

PMID42239085
PMCPMC13228497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.