Evidence map›Paper›PMID 42239043›Full record

ArticlebioRxiv : the preprint server for biology2026

Characterization of

Jeyashree Nathan Elango, Isaac H Shin, Anushree Gurjar, Amber R Krauchunas

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeyashree Nathan ElangoDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Isaac H ShinDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Anushree GurjarDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Amber R KrauchunasDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0003-0013-5258

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
Understanding synovial macrophage inflamm-aging within osteoarthritisP20GM139760 · NIGMS · UNIVERSITY OF DELAWARE · PI DAWN M ELLIOTT · 2021 to 2026
$19.1M
Spinning Disk Confocal and Single Molecule Localization MicroscopeS10OD030321 · OD · UNIVERSITY OF DELAWARE · PI CAPLAN, JEFFREY L · 2021 to 2021
$562k
NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM139760NIH HHS S10 OD030321
6 · The paper itself

Abstract

Fertilization is the process in which two specialized cells, the sperm and egg, interact, adhere, and fuse their membranes. This occurs in all sexually reproducing organisms. Several transmembrane and secreted proteins have been shown to be required for fertilization. Genetic mutations can alter these proteins and disrupt fertilization, leading to reduced or no offspring. When fertilization-specific sperm proteins are mutated, sperm production, motility, and activation are unaffected, but the sperm lose the ability to successfully fertilize an egg. In this study, we report on the sperm-specific protein SPE-40/FAM187, which is a single-pass transmembrane protein with an immunoglobulin-like domain. When

Indexed as

FAM187fertilizationfertilization synapseSPE-40sperm

Identifiers

PMID42239043
PMCPMC13228459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.