ArticleJADA foundational science2023
Analysis of the transparent surface layer formed at the surfaces of arrested enamel caries lesions with tomographic imaging methods.
Article in JADA foundational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Photonic Methods for the Assessment of Lesion Activity.Diagnostics (Basel, Switzerland) · 2026Review
Corrections and comments
- Erratum issuedCorrection.2024
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Optical coherence tomography (OCT) can acquire high-resolution images of lesion structure in vivo to assess lesion activity. The surface layers of arrested enamel caries lesions (ECLs) have a higher mineral content than the lesion body with a reduced porosity that inhibits the penetration of fluids into the lesion and appears with reduced reflectivity OCT. This study aimed to use microcomputed tomography (microCT) to measure the mineral content of the transparent surface layer (TSL) that appears on OCT images. Methods: OCT and microCT were used to measure the reflectivity and relative mineral density profiles of 20 bovine enamel samples that had simulated arrested ECLs, 44 extracted teeth with 17 proximal ECLs, 10 occlusal ECLs, and 17 lesions caused by fluorosis. TSL thickness (OCT), surface layer thickness (microCT), and the minimum and maximum densities of the TSLs were determined from matched OCT and microCT profiles. Results: For all samples, the TSL thickness measured with OCT was significantly less than the surface layer thickness measured with microCT ( Conclusions: The maximum mineral densities of the TSL measurable with OCT approach those of sound enamel suggesting that almost complete remineralization has occurred in the TSLs. This study provides further confirmation that the presence of a TSL in OCT images is a key indicator of lesion arrest.
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