Evidence map›Paper›PMID 42238965›Full record

ArticleAmerican heart journal plus : cardiology research and practice2026

Ventricular preexcitation-induced subclinical LV dysfunction: Insights from pressure-strain loop imaging.

Mingxia Li, Fen Chen, Jing Yao, Xinmin Chen, Xiaoxian Wang, Beibei Ge, Fang Xu, Pingyang Zhang, Shukui Wang

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In one paragraph

Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingxia LiDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210008, China.
Fen ChenDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Jing YaoDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Xinmin ChenDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Xiaoxian WangDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Beibei GeDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Fang XuDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Pingyang ZhangDepartment of Echocardiography, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210006, China.
Shukui WangDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ventricular preexcitation causes subclinical LV dysfunction despite preserved LVEF. Pressure-strain loop (PSL) analysis, a novel method, sensitively quantifies myocardial work to assess such functional alterations. This study evaluated global and segmental myocardial work alterations by PSL in these patients.MethodsSeventy-seven patients with ventricular preexcitation (stratified into right-AP [ Results: Septal AP and right AP demonstrated significantly increased global and basal-middle ventricular WW along with reduced WE compared to controls (all Conclusion: PSL analysis effectively identifies subclinical left ventricular dysfunction in ventricular preexcitation patients with preserved LVEF, particularly pronounced in right-sided and septal accessory pathway subgroups. Ventricular mechanical dyssynchrony emerges as a key mechanistic contributor to these functional impairments, highlighting its pivotal role in early-stage electromechanical uncoupling.

Indexed as

Left ventricular dysfunctionMyocardial workPressure-strain loopSpeckle tracking echocardiographyVentricular preexcitation

Identifiers

PMID42238965
PMCPMC13226251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.