Evidence map›Paper›PMID 42238780›Full record

ArticlePublic health weekly report2026

Analysis of Clinical Characteristics and Treatment Efficacy in the Korean Hepatitis B Cohort.

TaeYong Kim, Jae Seung Lee, Oeuk Jeong, Jeong Gyu Lee, Seungmi Choi, Sangmi Ryou, MinJin Go, Jungyeon Kim

Abstract read
In one paragraph

Article in Public health weekly report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

TaeYong KimDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID 0009-0000-1975-0221
Jae Seung LeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-2371-0967
Oeuk JeongDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0001-7415-377X
Jeong Gyu LeeDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0002-7213-6797
Seungmi ChoiDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0009-0004-8677-5823
Sangmi RyouDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0001-9997-9420
MinJin GoDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0002-6888-3765
Jungyeon KimDivision of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0003-2732-1544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The Korea hepatitis B cohort study is a prospective cohort established to analyze the epidemiological characteristics and treatment outcomes of individuals with chronic hepatitis B virus (HBV) infection in the Republic of Korea (ROK). This study aims to provide evidence to support HBV control, prevention strategies, and national policy development. Methods: Adults aged ≥19 years with chronic hepatitis B were enrolled at five regional medical institutions across ROK. Additional blood samples were collected from participants who consented to biospecimens donation. This prospective observational study did not interfere with routine clinical care. Data on antiviral treatment, treatment continuation, and liver-related outcomes, including hepatocellular carcinoma, were collected. Results: Between 2015 and 2024, a total of 3,221 participants were enrolled in the study. After excluding 422 individuals who were lost to follow-up, clinical data from 2,799 participants were collected. On average, 4.2 longitudinal blood samples per participant were obtained at 6- to 12-month intervals. The cohort exhibited epidemiological patterns consistent with previously reported trends in the ROK. The use of effective antiviral therapy was associated with better management of chronic hepatitis B. Conclusions: The continuation of this study will enable systematic and efficient monitoring of the current status and long-term clinical outcomes of patients with chronic hepatitis B. These findings are expected to inform revisions of national clinical practice guidelines and support the development of public health policies in the ROK.

Indexed as

Cohort studiesHepatitis BHepatitis B, chronicHepatitis B virus

Identifiers

PMID42238780
PMCPMC13228893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.