Evidence map›Paper›PMID 42238738›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2026

Evaluation of antimicrobial orders with expanded indication for use.

Michael Carlone, Jill Wesolowski, Samantha Loutzenheiser, Chanda Mullen, Steven Gordon, Thomas Fraser, Andrea M Pallotta

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael CarloneCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.ORCID https://orcid.org/0009-0002-5981-0203
Jill WesolowskiCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.
Samantha LoutzenheiserCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.ORCID https://orcid.org/0000-0003-3769-9567
Chanda MullenCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.ORCID https://orcid.org/0000-0003-4235-4547
Steven GordonCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.
Thomas FraserCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.
Andrea M PallottaCleveland Clinic Main Campus Hospital: Cleveland Clinic, Cleveland, USA.ORCID https://orcid.org/0000-0002-3960-7155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the impact of requiring infectious source selection on systemic antimicrobial orders for stewardship tracking. Design and Setting: Multicenter, health system quality improvement project across 17 hospitals and 21 emergency departments. Methods: All inpatient and ED antimicrobial orders with an indication between September 1 and September 30, 2024 were analyzed. Primary outcome: Prevalence of selected infectious sources. Secondary outcomes: indication frequency, free-text use, and concordance between selected and documented sources in 500 random orders. Results: Among 57,118 orders, empiric indication was most common (71%). Top sources: respiratory (23%), urinary/renal (19%), skin/soft tissue (16%). Concordance was 95%. Free-text entries (2.6%) often matched existing options; dental/oral emerged as a new category. Conclusion: Infectious source selection was evaluated and supports future targeted stewardship interventions.

Identifiers

PMID42238738
PMCPMC13227120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.