Evidence map›Paper›PMID 42238679›Full record

ReviewFrontiers in radiology2026

Antibiotic prophylaxis in percutaneous nephrostomy placements and replacements for malignant urinary tract obstruction. Retrospective cohort study with systematic review and meta-analysis.

Jeferson Rodrigo Zanon, Thiago Morais Santos, Henrique Durante, Welinton Yoshio Hirai, Marcelo Jenné Mimica, José Humberto Tavares Guerreiro Fregnani, Ricardo Dos Reis

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06801405 (Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction. A Retrospective Cohort Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06801405 completednot on this map

Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction. A Retrospective Cohort Study

TypeobservationalSponsorBarretos Cancer HospitalRan2021 to 2024Enrolled320ConditionsUreteral Obstruction, Neoplasms, Acute Kidney Injury, NephrostomyArmsantibiotic prophylaxis
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeferson Rodrigo ZanonNephrology and Palliative Care Departments of the Jales Cancer Hospital (a Barretos Cancer Hospital Unit-Pius XII Foundation), Jales, São Paulo, Brazil.
Thiago Morais SantosInterventional Radiology Department of the Jales Cancer Hospital (a Barretos Cancer Hospital Unit-Pius XII Foundation), Jales, São Paulo, Brazil.
Henrique DuranteInterventional Radiology Department of the Barretos Cancer Hospital (Pius XII Foundation), Barretos, São Paulo, Brazil.
Welinton Yoshio HiraiEpidemiology and Biostatistics Center of the Barretos Cancer Hospital (Pius XII Foundation), Barretos, São Paulo, Brazil.
Marcelo Jenné MimicaMicrobiology, Pathological Sciences, and Pediatrics Departments of the Santa Casa de Misericórdia de São Paulo Medical School, São Paulo, São Paulo, Brazil.
José Humberto Tavares Guerreiro FregnaniProfessor at the Postgraduate Program of the Barretos Cancer Hospital (Pius XII Foundation) and Superintendent of Education of the A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
Ricardo Dos ReisDepartment of Gynaecological Oncology-Chair; Director of the Educational and Research Institute, and Pro-Rector of the Postgraduate Program of the Barretos Cancer Hospital (Pius XII Foundation), Barretos, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Percutaneous nephrostomy (PN) can lead to urinary tract infections (UTIs), but these can be prevented by administering antibiotics. However, the effectiveness of this approach is debated. Methods: To evaluate the association between PN-related UTIs and antibiotic prophylaxis in cancer patients. This is a hybrid study was designed. A retrospective cohort study was conducted on cancer patients requiring PN, comparing antibiotic prophylaxis with no prophylaxis. The outcome, UTI, was measured up to seven days after the procedure. This cohort study was included in a systematic review and meta-analysis, for which random-effects models were used to synthesize the outcomes. Results: 734 PN procedures were performed. The UTI rate following antibiotic prophylaxis was 0/158 for catheter placement and 3/66 (4.5%; Discussion: Antibiotics may only protect against UTIs during PN catheter placement, but this was not confirmed by the meta-analysis. A randomized clinical trial is needed. Conclusion: Antibiotics may only protect against UTIs during PN catheter placement, but this was not confirmed by the meta-analysis. A randomized clinical trial is needed. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42021231063, ClinicalTrials.gov NCT06801405 and PROSPERO CRD42021231063.

Indexed as

acute kidney injuryantibiotic prophylaxisneoplasmsnephrostomypercutaneousureteral obstructionurinary tract infections

Identifiers

PMID42238679
PMCPMC13226567

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.