Evidence map›Paper›PMID 42238662›Full record

ReviewJADA foundational science2022

Development of standard protocols for biofilm-biomaterial interface testing.

Fabian Cieplik, Conrado Aparicio, Jens Kreth, Gottfried Schmalz

Erratum issuedAbstract readReview
In one paragraph

Review in JADA foundational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Antibiofilm and antibacterial effects ofBiomaterial investigations in dentistry · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Guidance on biomaterials for periodontal tissue regeneration: Fabrication methods, materials and biological considerations.Dental materials : official publication of the Academy of Dental Materials · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Immunomodulatory IL-23 receptor antagonist peptide nanocoatings for implant soft tissue healing.Dental materials : official publication of the Academy of Dental Materials · 2023
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Fabian CieplikDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Conrado AparicioDepartment of Odontology, Barcelona-Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Jens KrethDepartment of Restorative Dentistry, Oregon Health & Science University, Portland, OR.
Gottfried SchmalzDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral biofilm is associated with the most common oral diseases such as caries, periodontitis, and peri-implantitis. It is also linked to failures of dental treatment approaches (eg, direct or indirect restorations because of adjacent caries). Therefore, the development of materials with antibacterial properties is desirable. However, the design of meaningful tests to confirm such properties faces severe problems because of the complexity of the interaction of materials with the oral biofilm. Furthermore, owing to practical reasons, such tests need to be performed in vitro. In contrast, there is a need for predictive data that are comparable between different laboratories. Therefore, standardization of such tests has been advocated. The International Organization for Standardization (ISO) with its Technical Committee 106-Dentistry may be the relevant platform for this purpose. A standard (ISO 3990) is being developed for testing the antibacterial properties of dental restorative materials. This standard defines basic requirements for sample preparation, selection of bacterial strains, test methods and assessment, and reporting of results. It is considered to be the first step, and regular revisions are planned as new scientific evidence emerges. The support of the scientific communities providing multidisciplinary input is needed.

Indexed as

Antibacterialdental materialISO standardsmicrobiologystandardization

Identifiers

PMID42238662
PMCPMC13229039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.