Evidence map›Paper›PMID 42238651›Full record

ArticleReviews in cardiovascular medicine2026

Study on the Role and Mechanism of γδ T Cells in Atherosclerosis Under a High-Fat Diet.

Qinning Zhang, Xiaoxu Zhang, Meng Cao, Junbai Ma, Ru Yan, Hao Wang, Shaobin Jia

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qinning ZhangThe First Clinical College of Ningxia Medical University, General Hospital of Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0009-0007-3303-9728
Xiaoxu ZhangDepartment of Gastroenterology, General Hospital of Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0009-0000-0009-798X
Meng CaoDepartment of Clinical Nursing, School of Nursing, Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0009-0006-0996-0421
Junbai MaDepartment of Pathogenic Microbiology and Immunology, Institute of Basic Medical College, Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0009-0009-2784-6819
Ru YanSchool of Laboratory Medicine, Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0009-0004-4743-839X
Hao WangSchool of Laboratory Medicine, Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0000-0002-5776-8681
Shaobin JiaDepartment of Cardiovascular Medicine, General Hospital of Ningxia Medical University, 750001 Yinchuan, Ningxia, China.ORCID https://orcid.org/0000-0002-8545-1067

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate the effects of γδ T cell inhibition under a high-fat diet (HFD) on metabolic function, immune inflammation, gut microbiota, and atherosclerosis (AS) progression in Methods: Results: The HFD activated γδ T cells and increased pro-inflammatory cytokines in Conclusion: The γδ T cells contribute to AS development under the HFD. Inhibition of γδ T cells reduces inflammation, improves gut microbiota composition, and attenuates atherosclerosis progression.

Indexed as

atherosclerosisgut microbiotahyperlipidemiainflammatory cytokinesγδ T cells

Identifiers

PMID42238651
PMCPMC13227357

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.