Evidence map›Paper›PMID 42238516›Full record

ArticleSynthetic and systems biotechnology2026

Enhanced production of l-histidine in

Bo Zhang, Xintian Liu, Tianjun Zhao, Jinkang Hao, Zejian Wang, Menglei Xia, Ning Chen, Xiaonan Wang, Xiaoguang Fan

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bo ZhangCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Xintian LiuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Tianjun ZhaoCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Jinkang HaoCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Zejian WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.
Menglei XiaCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Ning ChenCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Xiaonan WangCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
Xiaoguang FanCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-Histidine is an essential amino acid with important applications in pharmaceuticals and nutrition, highlighting the demand for efficient microbial production platforms. This study developed a high-performance

Indexed as

CER-Controlled fermentationEscherichia colil-histidineMachine learning-guided transporter discoveryNon-model microbial mining

Identifiers

PMID42238516
PMCPMC13226134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.