Evaluation of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Biomarkers in Missed Abortions.

Objectives: To evaluate the usability and clinical significance. Missed abortion, a common complication in early pregnancy. Diagnosis typically relies on ultrasonographic findings and clinical criteria. The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio have attracted considerable interest. Methods: A total of 120 women participated, with 60 diagnosed with missed abortion and 60 with healthy intrauterine pregnancy. This is a retrospective case-control study. Information for the study was gathered from patient file records. Mann-Whitney U Test was used. Logistic regression analysis assessed the magnitude and direction of the relationships between the variables. Results: The youngest participant was 23, while the oldest was 42. There was no significant difference in age between the two groups. Logistic regression analysis was conducted using the following variables: white blood cells, lymphocytes, monocytes, main platelet volume, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio. It was determined that WBC, Lymphocyte, Monocyte, NLR and PLR values can effectively predict cases of missed abortion ( Conclusion: Our study reinforces the hypothesis that inflammatory markers such as the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios could serve as accessible and cost-effective indicators of early pregnancy loss.