Evidence map›Paper›PMID 42238286›Full record

ArticleSaudi medical journal2026

Evaluating the Diagnostic Accuracy of Ultrasound and Clinical Predictors in Pediatric Acute Tip Appendicitis:

Abdullah M Abu Qarnayn, Saud A Aljadaan, Suliaman M Alaqeel, Faisal S Alshehri, Abdullrzak N Algosear, Waleed A Alharthi, Munirah A Alsukait, Kholoud S AlShaya

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Article in Saudi medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Abdullah M Abu QarnaynCollege of Medicine, Dar Al Uloom University.ORCID 0009-0007-5133-910X
Saud A AljadaanMinistry of National Guard Health Affairs, Department Of Pediatric Surgery.
Suliaman M AlaqeelMinistry of National Guard Health Affairs, Department Of Pediatric Surgery.
Faisal S AlshehriCollege of Medicine, Dar Al Uloom University.
Abdullrzak N AlgosearCollege of Medicine, Dar Al Uloom University.
Waleed A AlharthiCollege of Medicine, Dar Al Uloom University.
Munirah A AlsukaitKing Saud bin Abdulaziz University for Health Sciences.
Kholoud S AlShayaMinistry of National Guard Health Affairs, Department Of Radiology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examines the diagnostic accuracy of ultrasound (US) and the clinical characteristics of pediatric ATA. Acute tip appendicitis (ATA), a rare form of appendiceal inflammation confined to the distal tip, presents with atypical symptoms and is difficult to diagnose. The Confirmation often relies on imaging and surgical pathology. Methods: A Retrospective cross-sectional study conducted at a tertiary hospital in Riyadh, Saudi Arabia, from 2020 to 2024. Among 4,224 pediatric patients with acute appendicitis under 14 years, and our sample size of 59 patients were diagnosed with ATA by US. Firth logistic regression was used to reduce bias in the small-sample analysis. Results: Among 59 children diagnosed with acute tip appendicitis (ATA) by US, 32 were confirmed by pathology. Ultrasound demonstrated a sensitivity of 65.6%, specificity of 81.5%, and an area under the receiver operating characteristic curve (AUC) of 0.804. Firth logistic regression identified abdominal pain (adjusted odds ratio [Adj OR] = 12.7; 95% confidence interval [CI]: 0.918-183.2) as a positive predictor, while higher fever (Adj OR = 0.37; 95% CI: 0.151-0.765) was inversely associated with confirmed ATA. US accuracy was not significantly associated with a return to the emergency department within 30 days ( Conclusion: The ATA in children often lacks classic signs like high fever. US has high specificity but moderate sensitivity. Firth logistic regression was effective for analyzing small samples. Greater clinical awareness and optimized imaging use are needed for early detection and improved outcomes.

Indexed as

AppendicitisAbdominal PainAcute DiseaseAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleRetrospective StudiesROC CurveSaudi ArabiaSensitivity and SpecificityTertiary Care CentersUltrasonographyAbdominal painAcute tip appendicitisChildrenEmergency departmentFeverFirth logistic regressionUltrasound

Identifiers

PMID42238286
PMCPMC13227430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.