Evidence map›Paper›PMID 42238209›Full record

ArticleSaudi medical journal2026

COVID-19-Associated Rhabdomyolysis in Hospitalized Patients:

Paula Esquerdo-Serrano, Silvia Otero-Rodriguez, Hector Pinargote-Celorio, Sergio Reus, Esperanza Merino, José-Manuel Ramos-Rincón

Abstract read
In one paragraph

Article in Saudi medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paula Esquerdo-SerranoPneumology Department, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.
Silvia Otero-RodriguezInfectious Diseases Unit, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.ORCID 0000-0002-7801-5072
Hector Pinargote-CelorioInfectious Diseases Unit, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.ORCID 0000-0002-3300-5807
Sergio ReusInfectious Diseases Unit, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.ORCID 0000-0002-3320-9754
Esperanza MerinoInfectious Diseases Unit, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.ORCID 0000-0003-3854-4874
José-Manuel Ramos-RincónInfectious Diseases Unit, Dr. Balmis General University Hospital. Alicante Institute of Healthcare and Biomedical Research (ISABIAL), Alicante, Spain.ORCID 0000-0002-6501-9867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To determine the frequency of rhabdomyolysis in patients hospitalized with COVID-19 and to characterize their clinical features and outcomes. Methods: All adults admitted to the hospital were included in this single-center retrospective cohort study with COVID-19 at a tertiary care institution in Alicante, Spain, between March 2020 and March 2024. A creatine kinase (CK) threshold of 1000 U/L or higher was used to define rhabdomyolysis. Demographic, clinical, laboratory, treatment, and outcome data were collected. Patients with and without rhabdomyolysis were compared, and factors associated with in-hospital mortality (IHM) were analyzed. Results: Among 7,590 hospitalized COVID-19 patients, 20 developed rhabdomyolyses (cumulative incidence 0.26%; 95% CI 0.170.41). Most affected patients were male (85%), and male sex demonstrated an independent relationship with rhabdomyolysis (adjusted OR 4.35; 95% CI 1.2714.94). Acute kidney injury was observed in 60% of patients, and 15% required hemodialysis. IHM was markedly higher among patients with rhabdomyolysis than in those without (35% vs. 11.5%) (adjusted OR 4.24; 95% CI 1.4812.10). Conclusion: Rhabdomyolysis was an uncommon but severe complication of COVID-19, predominantly affecting men and frequently inked to acute kidney failure and high IHM.

Indexed as

COVID-19RhabdomyolysisAcute Kidney InjuryAdultAgedCreatine KinaseFemaleHospitalizationHospital MortalityHumansIncidenceMaleMiddle AgedRetrospective StudiesSARS-CoV-2SpainCreatine KinaseAcute kidney injuryCOVID-19HospitalizationMortalityRhabdomyolysis

Identifiers

PMID42238209
PMCPMC13217627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.