Evidence map›Paper›PMID 42238151›Full record

ArticleCureus2026

Punarnavayolepa Choornam in Iron Deficiency Anemia Management: Pharmaceutical Insights and Biological Activity.

Jyothish G Nair, Rajani Ts, Deepthy Mohan, Puthanpurakal Indu Chandrabose, Varsha Wilson, Atheena Biju Shyn, Remya Venugopala Menon, Ashi Augustine, Yadu Narayanan Mooss, Subrahmanya Kumar Kukkupuni and 3 more

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jyothish G NairAyurveda Biology, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Rajani TsAyurveda Biology and Holistic Nutrition, The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, IND.
Deepthy MohanPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Puthanpurakal Indu ChandrabosePhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Varsha WilsonPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Atheena Biju ShynBotany, Christ College (Autonomous), Irinjalakuda, Thrissur, IND.
Remya Venugopala MenonPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Ashi AugustinePhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Yadu Narayanan MoossPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Subrahmanya Kumar KukkupuniAyurveda Biology and Holistic Nutrition, The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, IND.
Sheela Karalam BPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.
Chethala N VishnuprasadAyurveda Biology and Holistic Nutrition, The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, IND.
Asish Gopinathan RemanikuttyPhytochemistry, Vaidyaratnam Ayurveda Research Institute, Thrissur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndigenous medical systems employ unique pharmaceutical techniques to meet the therapeutic needs. In the Indian System of Medicine,

methodsThe iron content in both raw and processed samples of PC was quantified using inductively coupled plasma mass spectrometry (ICP-MS). A simulated in vitro digestion model was employed to assess the release of bioavailable iron from the formulation. Subsequently, iron bioavailability was evaluated using the human colorectal adenocarcinoma cell line (Caco-2) cell model of human intestinal epithelium following the ferrozine method.

resultsPC preparation from leaves, whole plant, and roots of

conclusionTo conclude, the observations from our preliminary study provide a scientific rationale for this unique pharmaceutical preparation (PC) from a traditional school of Ayurveda, supporting its clinical application in IDA management.

Indexed as

ayolepamayurveda pharmaceuticsboerhavia diffusadrug designiron bioavailabilityiron deficiency anemiapunarnavayolepa choornamtraditional medicine

Identifiers

PMID42238151
PMCPMC13227311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.