Evidence map›Paper›PMID 42238028›Full record

ArticleBioactive materials2026

pH-responsive nano immunomodulator for rheumatoid arthritis therapy via macrophages pyroptosis inhibiting and reprograming.

Rui Wen, Haoyu Qiu, Pingli Dong, Lanling Dai, Xiaoqin Hu, Fang Lan, Yao Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui WenNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Haoyu QiuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Pingli DongNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Lanling DaiNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Xiaoqin HuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Fang LanNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Yao WuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current immunosuppressive therapies for rheumatoid arthritis (RA) are limited by substantial side effects, prompting the need for strategies that remodel the disease microenvironment via immunomodulation. RA progression is driven by a self-amplifying cycle fueled by elevated extracellular ATP (eATP), reactive oxygen species (ROS) and local acidosis. To disrupt this pathological loop, we developed an intelligent Ce-MOF@CaCO

Indexed as

ATP-Adenosine conversionNanozymePyroptosis inhibitionRheumatoid arthritisROS scavenging

Identifiers

PMID42238028
PMCPMC13226831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.