Evidence map›Paper›PMID 42237943›Full record

ArticleZoological research2026

Integrated transcriptomic analysis reveals lymphatic

Xue-Ting Chen, Bei-Bei Hu, Zhao Zhang, Zhong-Xiang Chen, Si-Lian Chen, Shu-Xin Su, Zhe Zhang, Cheng Huang, Lei Wang, Kaa-Seng Lai and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xue-Ting ChenCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Bei-Bei HuPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Zhao ZhangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhong-Xiang ChenPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Si-Lian ChenCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Shu-Xin SuCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhe ZhangDepartment of Cardiology, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, Guangdong 519000, China.
Cheng HuangDepartment of Cardiology, Fuwai Yunnan Cardiovascular Hospital, Cardiovascular Hospital Affiliated to Kunming Medical University, Kunming, Yunnan 650000, China.
Lei WangDepartment of Cardiovascular Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, China.
Kaa-Seng LaiPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Jun-Jie YangPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Ye WangPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Xiao-Dong FangBGI Research, Sanya, Hainan 572025, China.
Zhen ZhangPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Juan ShenBGI Research, Shenzhen, Guangdong 518083, China. E-mail: juan.shen@genomics.cn.
Min ZhangPediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China. E-mail: minzhang5099@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac lymphatic vessels are active regulators of immune surveillance and inflammatory resolution after myocardial injury. Intercellular adhesion molecule-1 (ICAM-1), a cell-surface glycoprotein broadly expressed in endothelial cells, mediates leukocyte adhesion and trafficking during inflammation; however, how

Indexed as

Intercellular Adhesion Molecule-1Lymphatic VesselsMyocardial InfarctionAnimalsEndothelial CellsGene Expression ProfilingGene Expression RegulationMaleMiceMice, KnockoutIcam1 protein, mouseIntercellular Adhesion Molecule-1Icam1Lymphatic endothelial cellsMyocardial infarctionSingle-cell RNA sequencingSpatial transcriptomic sequencing

Identifiers

PMID42237943
PMCPMC13647053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.