Evidence map›Paper›PMID 42237654›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2026

Healthy Dietary Patterns and Risk of Parkinson's Disease.

Xiao Chen, Hui Chen, Peilu Wang, Michael A Schwarzschild, Albert Y Hung, Xiang Gao, Alberto Ascherio, Mario H Flores-Torres, Kjetil Bjornevik

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Article in Movement disorders : official journal of the Movement Disorder Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao ChenDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2108-2215
Hui ChenDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Peilu WangDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Clinical Research Institute, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-5744-0259
Michael A SchwarzschildHarvard Medical School, Boston, Massachusetts, USA.
Albert Y HungHarvard Medical School, Boston, Massachusetts, USA.
Xiang GaoDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Clinical Research Institute, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-2617-6509
Alberto AscherioDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Mario H Flores-TorresDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Kjetil BjornevikDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough healthy dietary patterns have been suggested to be associated with decreased Parkinson's disease (PD) risk, their protective role remains uncertain.

objectiveTo examine associations between eight dietary patterns and PD risk in two United States (US) cohorts followed for up to 32 years.

methodsWe analyzed 70,973 women from the Nurses' Health Study and 45,820 men from the Health Professionals Follow-up Study. Dietary patterns were assessed every 4 years using food frequency questionnaires. Cox regression models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for PD across quintiles of cumulative average adherence.

resultsDuring follow-up, 579 women and 600 men developed PD. Higher adherence to dietary patterns was not associated with PD risk. Comparing the highest versus lowest quintile, HRs (95% CIs) were 1.01 (0.75-1.36) for the Alternative Healthy Eating Index-2010, 1.11 (0.91-1.35) for the Alternate Mediterranean Diet, 1.12 (0.69-1.79) for the Dietary Approaches to Stop Hypertension, 1.01 (0.84-1.22) for the healthful Plant-based Diet Index, 1.09 (0.90-1.32) for the Planetary Health Diet Index, 1.02 (0.84-1.24) for the Mediterranean-DASH Intervention for Neurodegenerative Delay diet score, 1.12 (0.90-1.38) for the reversed Empirical Dietary Inflammatory Pattern, and 0.99 (0.68-1.45) for the reversed Empirical Dietary Index for Hyperinsulinemia. In food-groups analyses, higher low-fat dairy intake was associated with higher PD risk (HR

conclusionsIn two US cohorts, adherence to eight healthy dietary patterns was not associated with PD risk. Although these patterns are associated with lower risk of several chronic diseases, they may be ineffective for PD prevention. © 2026 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Diet, HealthyParkinson DiseaseAdultAgedCohort StudiesDiet, MediterraneanFemaleFollow-Up StudiesHumansMaleMiddle AgedRisk FactorsUnited StatesAlternative Healthy Eating Indexdietary patternsMediterranean dietMIND dietnutritional epidemiologyParkinson's diseaseprospective cohort study

Identifiers

PMID42237654
PMCPMC13602294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.