Evidence map›Paper›PMID 42237403›Full record

SynthesisBMC psychology2026

Psychological interventions to alleviate death anxiety among patients with cancer: a systematic review and meta-analysis of randomized controlled studies.

Guiyun Wang, Jiaojiao Li, Jinnan Xiao, Yanxia Qi, Siyuan Tang, Jiaoyang Liu, Yuehua Han, Jinke Kuang, Wenjing Xu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guiyun Wang *School of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Jiaojiao Li *School of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Jinnan XiaoXiangya School of Nursing, Central South University, No; 172 Tongzipo Road, Yuelu District, Changsha, China. jnxiao2021@csu.edu.cn.
Yanxia QiSchool of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Siyuan TangXiangya School of Nursing, Central South University, No; 172 Tongzipo Road, Yuelu District, Changsha, China.
Jiaoyang LiuSchool of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Yuehua HanSchool of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Jinke KuangSchool of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.
Wenjing XuSchool of Nursing, Shandong Xiehe University, No; 6277 Jiqing Road, Licheng District, Jinan City, Shandong Province, China.

Funding

Research Project of Hunan Nursing Association Grant No.: HNKYQ202302Youth Innovation Technology Project of Higher School in Shandong Province No.: 2023KJL031
6 · The paper itself

Abstract

objectiveDeath anxiety is a common psychological distress in cancer patients and is associated with reduced quality of life. However, the efficacy of current psychological interventions for relieving this symptom remains unclear. This study aims to assess the effectiveness of psychological interventions in alleviating death anxiety among cancer patients and explore key effective intervention components.

methodsA systematic review of randomized controlledstudies. DATA SOURCES: Eight databases (PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CNKI, Wanfang, and VIP) were searched from inception to February 28, 2025. The Cochrane Risk of Bias 2 (RoB 2.0) tool was used to assess the risk of bias in the included studies.

resultsNine papers involving 1,024 cancer patients were included. According to intervention components, the studies were divided into two categories: (1) Exploration of Life Meaning Interventions (ELMI) and (2) Cognitive Restructuring Interventions (CRI). Meta-analysis showed ELMI had a statistically significant but modest effects on death anxiety (SMD: - 0.17, 95% CI: (-0.32, - 0.01), P = 0.03). Narrative synthesis suggested that CRI may alleviate death anxiety among cancer patients. GRADE assessment rated the evidence for death anxiety as very low.

conclusionsThe effect of psychological interventions on alleviating death anxiety in cancer patients remains inconclusive. ELMI showed a statistically significant but modest effect, while evidence for CRI was inconsistent. Further high-quality studies with larger samples, standardized protocols, and longer follow-up are needed to explore combined or personalized intervention strategies.

trial registrationThe study protocol for this systematic review has been registered in PROSPERO(CRD420251169425).

Indexed as

AnxietyAttitude to DeathNeoplasmsPsychosocial InterventionHumansRandomized Controlled Trials as TopicCancerDeath anxietyPsychological interventionsRandomized controlled studiesSystematic review

Identifiers

PMID42237403
PMCPMC13450554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.