Evidence map›Paper›PMID 42237365›Full record

ArticleBMC research notes2026

Prognostic value of the hemoglobin-to-red cell distribution width ratio (HRR) in predicting mortality and rehospitalization in patients with chronic heart failure.

Samira Arami, Bahare Gholami Chaboki, Negin Letafatkar, Arsalan Salari, Seyed Mehdi Mousavi, Zahra Ahmadnia

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Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Samira AramiCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Bahare Gholami ChabokiCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Negin LetafatkarGastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Arsalan SalariCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Seyed Mehdi MousaviCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Zahra AhmadniaCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. zahmadnia1365@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeart failure (HF) represents a significant and growing global health burden. The hemoglobin-to-red cell distribution width ratio (HRR), a novel composite marker integrating oxygen-carrying capacity (hemoglobin) and red cell distribution width (RDW), has shown prognostic value in various diseases, but its role in chronic HF remains underexplored. This study aimed to evaluate the prognostic value of HRR for mortality and 12-month rehospitalization in patients with chronic HF.

resultsA total of 419 patients with chronic heart failure were included in the analysis. A lower HRR was independently associated with increased all-cause mortality. Each unit increase in HRR was associated with a 17% reduction in mortality odds (Adjusted OR: 0.83; 95% CI: 0.73-0.95; p = 0.006). This inverse relationship was significant in anemic patients but not in non-anemic patients. In contrast, HRR was not associated with rehospitalization in the overall or anemic populations, but a higher HRR was significantly associated with reduced rehospitalization odds in non-anemic patients (Adjusted OR: 0.81; 95% CI: 0.66-0.99; p < 0.05).

Indexed as

Erythrocyte IndicesHeart FailureHemoglobinsPatient ReadmissionAgedAnemiaChronic DiseaseFemaleHumansMaleMiddle AgedPrognosisHemoglobinsHeart failurePrognosisRed blood cell distribution width

Identifiers

PMID42237365
PMCPMC13449320

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