Evidence map›Paper›PMID 42237012›Full record

ArticleNeuroscience bulletin2026

Space-Dependent Oviposition Preference in Drosophila.

Xiangbin Su, Yicong Jia, Can Gao, Shanshan Hu, Wenjing Ye, Sihui Jin, Zijian Liang, Dongliang Chen, Jie Chen, Qionglin Peng and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiangbin SuThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Yicong JiaCollege of Life Sciences, Hubei University, Wuhan, 430062, China.
Can GaoThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Shanshan HuDepartment of Neurobiology, Department of Neurology of Sir Run Shaw Hospital and School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Wenjing YeDepartment of Neurobiology, Department of Neurology of Sir Run Shaw Hospital and School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Sihui JinThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Zijian LiangThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Dongliang ChenThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Jie ChenCollege of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, China.
Qionglin PengThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China.
Fang GuoDepartment of Neurobiology, Department of Neurology of Sir Run Shaw Hospital and School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou, 310058, China. gfang@zju.edu.cn.ORCID http://orcid.org/0000-0002-0433-9808
Shun-Fan WuCollege of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, China. wusf@njau.edu.cn.ORCID http://orcid.org/0000-0003-0096-147X
Yufeng PanThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, 210096, China. pany@seu.edu.cn.ORCID http://orcid.org/0000-0002-1535-9716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oviparous animals optimize egg-laying site selection through multimodal integration of environmental cues. Previous studies have established Drosophila as an ideal model to study egg-laying decision-making based on evaluating food ingredients and hardness, but how spatial cues direct oviposition strategies remains poorly understood. Here, we established behavioral assays for studying space-dependent oviposition preference in Drosophila, and identified Pickpocket 26 (Ppk26), a member of the DEG/ENaC family, regulating oviposition preference on waved versus flat surfaces. ppk26-expressing sensory neurons respond to ovipositor contact and specifically mediate flatness-based oviposition preference, but not other spatial or non-spatial preferences. Moreover, we found that a waved surface allowed more contact with flies' ovipositor to preferentially activate ppk26-expressing neurons and facilitate egg insertion into the waved oviposition site. These findings highlight a role for spatial cues in oviposition decision-making and establish ppk26 as a key mediator of contact-based spatial encoding during oviposition site selection.

Indexed as

Decision-makingDrosophila melanogasterMechanosensationOviposition behaviorppk26Spatial cues

Identifiers

PMID42237012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.