ArticleScientific reports2026
Kinematic analysis of multisensory integration and sensory load induced fatigue in migraine.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with migraine frequently experience performance deterioration during repetitive sensory tasks. This study aimed to investigate the behavioral and temporal dynamics of this deterioration under multisensory load. We analyzed sensory profile assessment and kinematic data during a continuous sensorimotor tracking task with sequentially added visual, auditory, semantic-numeric, and somatosensory stimuli from 36 female participants (15 interictal migraine without aura (MwoA), mean age 21.6 ± 3.36 years; 21 healthy controls, mean age 20.81 ± 0.93 years). Kinematic data were analyzed using linear mixed-effects models, focusing on tracking error and temporal lag. During the unimodal visual baseline, sensorimotor skill acquisition was intact without any temporal lag in the MwoA group. Adding sensory cues reduced tracking error in the healthy group, indicating facilitated multisensory integration, while no change was observed in the MwoA group. Addition of sensory cues triggered a progressive phase lag; the final addition of continuous somatosensory input resulted in a significant temporal delay in the MwoA group. Cumulative temporal delay positively correlated with the patients' sensory sensitivity score. Collectively, these findings indicate that the interictal migraine brain struggles to align and integrate complex, cross-modal information temporally, suggesting a critical vulnerability to processing fatigue under continuous environmental load.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.